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BriteVu used to study Traumatic Brain Injury

Jan 9, 2019/ Comments 0 / in Mammals, standard

Dr Gama-Sosa and his team (Icahn School of Medicine at Mount Sinai) completed and published a ground-breaking study that better characterizes the effects of traumatic brain injury in rats. The animals were humanely subjected to low level blast injury that did not result in any obvious general brain histopathology. The injury mimicked the low-level blast exposure that military personnel may be exposed to in combat situations- not the major blast injury that results in obvious physical trauma. The research team…

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Customer Reviews

Frank van Breukelen, PhD

University of Nevada, Las Vegas
Scott Echols is a rare individual in the world of laboratory innovation. His genuine curiosity and desire for science outweigh other motivations. He wants to see good science get done. To that end, Scott will do whatever it takes. The product (BriteVu) is great but I think what makes everything successful is Scott’s enthusiasm and diligence.

Tenrec- Dr Frank van Breukelen
Dr. James Brown BVSc, Dip. ACT, ACVS

Marion duPont Scott Equine Medical Center Virginia-Maryland regional college of Veterinary Medicine
As an equine surgeon and clinical researcher with a focus on the equine head, it is readily apparent that many diseases involve vasculature. Through a research project aimed at treatment of orosinus fistula, we became particularly interested in the vascular anatomy of the equine oral cavity. Information regarding vasculature anatomy beyond the major vessels was limited. We learnt of Dr. Scott Echols and his research into terminal vascular contrast agents through our mutual association with Epical Medical Imaging. Scott had a wealth of knowledge regarding the study of vasculature and we quickly began to collaborate on a project to use BriteVu in the horse. He was able to guide us in developing protocols and traveled to be on site to oversee the first ever perfusion trial in the horse using BriteVu. The BriteVu study was an outstanding success delivering amazing vascular detail that we desired for our research. Scott was instrumental to our success, guiding us in the procedure, reviewing CT images, and leading us to software engineers that could further develop our data. Scott has a genuine vested interest in the successful outcome of the project, and it could not have had a better collaboration experience.
Brian Zenger, MD-PhD Candidate

University of Utah School of Medicine- Dept of Biomed Engineering
BriteVu is a superior product that gives accurate localization of fine vascular structure following our experiments. The compound is stable, easy to use, and nontoxic. This product is vital for our research to visualize the coronary vasculature of the heart. Dr. Scott Echols is an excellent resource and has answered many questions and helped us design a protocol that fits our unique experimental needs. BriteVu truly is a fantastic product with great company support.
Nikita Kondratiev

Senior Research Associate- Keros Therapeutics
BriteVu proved to be an practical and versatile choice for a contrast agent. It was used in a series of studies involving perfusions as part of an effort to characterize the effect of a commercial drug candidate on vascular development. Ease of preparation and cost efficiency make it an excellent option for exploratory research.
John G. Capano

Department of Ecology and Evolutionary Biology, Brown University
BriteVu has been a tremendous tool to visualize and measure cardiorespiratory vascularization. The solution was simple to prepare and Dr. Echols was extremely supportive and helpful in helping design a protocol for my needs. The CT images showed outstanding detail and were easy to segment and analyze with existing software. Overall BriteVu is a fantastic product and the company provides exceptional service.

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