BriteVu high radio density contrast agent | Scarletimaging.com

BriteVu

5.00 out of 5

$134.99

Buy 4 jars and get 10% off product price
($122 per 170g jar)

Buy 5 or more jars and get 20% off!
($108 per 170g jar)

SKU: 040232483479 Category:

Description

BriteVu is a high radiodensity contrast media to be used only in terminal subjects. Each 8oz jar contains 170 g of powdered material. BriteVu (1 part in grams) is mixed with water and other select water soluble solvents (2.75-3.0 parts in cc at full strength). When properly mixed at full strength, each jar can produce approximately 550-650 cc of smooth white liquid contrast material. This is enough material to perfuse 6-7 adult mice and 5-6 adult rats (< 300 g).

The contents of each bag are mixed per the directions below and infused into the test subject. Infuse the product into the system being evaluated. For example, for blood vessel evaluation infuse BriteVu intravascularly. As a note, protocols can vary significantly based on intended results. The protocol below provides the most common guidelines for use.

The subject is then later scanned using radiographs, computed tomography (CT) or magnetic resonance imaging (MRI) depending on the study.

For Best Results Mix 1 Part BriteVu (in grams) to 2.75-3.0 Parts Water (in cc):

(As an example, mix 25 grams of BriteVu in 69-75 cc of water)

  1. Heat the appropriate amount of water in a beaker with mixing rod to at least 40-45 deg C on a stirring hot plate.
  2. Mix the appropriate amount of BriteVu into the heated water bath with mixing rod stirring such that all powder goes into solution.
  3. Heat solution to 70-80 deg C for at least 10 minutes.
  4. Immediately perfuse the entire solution at 50-70 deg C into the deceased subject.
  5. Further cool the subject at room temperature, or in a cold water bath, for 45-60 minutes to ensure solidification prior to imaging.
  6. If fixation is desired, immerse whole test subject or selected tissues in fixative after perfusion with BriteVu.
  7. Protocols can vary based on intended results. Go to Usage for more details.

Item #: 040232483479

BriteVu SDS

BriteVu advantages
Comparison of Commercially Available Terminal Vascular Contrast Agents

***PLEASE NOTE: Customer is responsible for customs duties and taxes for international shipments.

Additional information

Weight 200 g
Dimensions 2.75 x 2.75 x 3 in

3 reviews for BriteVu

  1. Rated 5 out of 5

    scarlet

    BriteVu is one of the most exciting and innovative things to happen to the field of anatomy in a long time. Everything about BriteVu is an upgrade from the current products out there for vascular imaging, and the staff at Scarlet Imaging are both wonderful to work with and willing bend over backwards to help facilitate the research needs of their clients.

    Emma R. Schachner, PhD

    Laboratory for Equine and Comparative Orthopedic Research, Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University

  2. Rated 5 out of 5

    scarlet

    BriteVu provides remarkable vascular contrast in X-ray images, particularly across small-vessel lumina. It’s an easy-to-use visualization tool with predictably clear results.

    Paul M. Gignac, PhD

    Department of Anatomy & Cell Biology, Oklahoma State University Center for Health Sciences

  3. Rated 5 out of 5

    scarlet

    An Aneurism is a localized, blood-filled balloon-like bulge in the wall of a blood vessel. When the size of an aneurysm increases, there is a significant risk of rupture, resulting in severe hemorrhage, and other complications, even death. The exact cause of an aneurysm is unclear. Incidence rate of aneurysm in infant could be up to 3.6%, and often associated with other congenital heart defects. In adults, aneurysm formation is probably the result of multiple factors affecting the arterial segment and its local environment. To understand the morphogenesis of cardiac anomalies, specifically the homeostasis of the blood flow resulting from an aneurysm, part of our research includes the injection of BriteVu high radiodensity contrast media to understand the 3-dimension cardiovascular system resulted from the disease via micro-computed tomography (µ-CT). Since we are utilizing chick embryo to study the early cardiovascular development, the BriteVu contrast media is readily soluble in water and fairly stable in the colloidal liquid when maintained in a warm incubator for a long period of time. This is essential for easy injection to the tiny vascular system since the whole embryo could be merely few millimeter of blood volume. Most of all, the media provides fine details of the heart structure and its vasculature from µ-CT scan.

    Norman Hu, MS

    Department of Pediatrics, University of Utah

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