Rabbit Anatomy Highlighted with BriteVu

Rabbit Anatomy Highlighted with BriteVu

European rabbit (Oryctolagus cuniculus) anatomy highlighted with BriteVu.  Rabbits are found throughout nature, research and as popular pets.  Records from Pliny the Elder in the first century BC note keeping rabbits. These and other records suggest rabbits have been with humans for over 2000 years.  Even with the long history of keeping rabbits, we still have a lot to learn about their anatomy and care.  This whole body BriteVu perfusion beautifully highlights the vascular anatomy of an adult, intact, female…

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Common Tenrec Anatomy BriteVu Study!!

Common Tenrec Anatomy BriteVu Study!!

Common tenrec (Tenrec ecaudatus) vascular anatomy as seen with BriteVu. Study conducted at University of Nevada Las Vegas.  Tenrecs are unusual mammals with unique physiology and anatomy and originate primarily from Madagascar.  Dr Frank van Breukelen and his team at UNLV are the leading researchers studying these strange animals.  This tenrec is the first ever to undergo a whole body BriteVu contrast perfusion.  Further, this project was a collaborative effort between UNLV, Touch of Life Technologies and Scarlet Imaging.  The…

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Pony BriteVu Contrast Study

Pony BriteVu Contrast Study

A whole pony perfused with BriteVu.  Procedure performed at the Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine.  BriteVu and BriteVu Enhancer were both used in this novel whole body preservation and contrast perfusion.  This represents the first time such a technique was used in an equine species.  A vast amount of data was generated as the pony was perfused head to toe producing vascular contrast down to the capillaries. Dr James Brown and his staff…

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BriteVu used to study Traumatic Brain Injury

BriteVu used to study Traumatic Brain Injury

Dr Gama-Sosa and his team (Icahn School of Medicine at Mount Sinai) completed and published a ground-breaking study that better characterizes the effects of traumatic brain injury in rats.  The animals were humanely subjected to low level blast injury that did not result in any obvious general brain histopathology. The injury mimicked the low-level blast exposure that military personnel may be exposed to in combat situations- not the major blast injury that results in obvious physical trauma.  The research team…

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Rat Head with Tongue Blood Supply

Rat Head with Tongue Blood Supply

A whole rat head was perfused with BriteVu and multiple areas were evaluated for their blood supply.  As several researchers are currently studying the blood supply to the jaw and oral cavity, this area has been of interest.  Here the rat head has been digitally ‘cut’ to show the head split down the middle from front (rostral) to back (caudal).  The highly vascular tongue is shown just behind (to the right of) the teeth.  Also the vasculature to the lower…

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Rat Ovaries and Uterine Horns Perfused with BriteVu

Rat Ovaries and Uterine Horns Perfused with BriteVu

After total body perfusion with BriteVu, the rat’s ovaries, uterine horns and uterus were removed for individual micro CT scanning (35µm).  The body of the uterus is to the left and can be seen separating into the individual left and right uterine horns and finally ending in the ovaries (far right).  The blood supply to the uterine horns and ovaries are readily apparent and in stunning detail.  Such studies can be used to understand blood flow to the female reproductive…

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Mouse Liver Perfused with BriteVu + Metaflow

Mouse Liver Perfused with BriteVu + Metaflow

As different researchers have been requesting specific features (when looking at vascular structures), our team has been using a variety of techniques to improve image quality with BriteVu.  This image shows the caudal side of a mouse liver perfused with BriteVu and Metaflow (The Dodge Company, http://www.dodgeco.com/). The addition of metaflow improved perfusion, including continuity of filling, of some vascular organs.  For more details as to how we used Metaflow with BriteVu perfusions, please ‘Contact’ us.  Scanned on Siemens Inveon…

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Rat Kidney BriteVu Perfusion for Research

Rat Kidney BriteVu Perfusion for Research

BriteVu perfused rat kidney CT scanned at 30 µm. Courtesy of the Head Injury and Vessel Biomechanics Lab at the University of Utah. The whole rat was perfused for a brain vasculature study.  However all of the tissues were well infiltrated with BriteVu creating incredible perfusions throughout the body.

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Rat Eye BriteVu Arteriovenogram

Rat Eye BriteVu Arteriovenogram

Window to the soul.  An arteriovenogram reached the eye of a rat and, combined with micro CT, produced a detailed map of the blood supply to and within the eye.  The central (black) portion represents the iris which is immediately outlined by the blood supply to the iris.  The back half of the eye has been digitally removed to create a clearer picture.  CT scan at 10µm.  Courtesy of the Head Injury and Vessel Biomechanics Lab at the University of…

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Rat Heart Perfused with BriteVu CT Contrast Agent

Rat Heart Perfused with BriteVu CT Contrast Agent

Rat heart perfused with BriteVu contrast agent. As a part of a study at the Head Injury and Vessel Biomechanics Lab at the University of Utah, the whole rat was perfused and individual organs were CT scanned for detailed analysis. The 10 µm CT scan shows individual blood vessels in the heart muscle and on the outside (especially along the coronary groove). By understanding vascular flow, researchers can determine areas of increased and decreased blood supply to different parts of the…

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